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1

Paradigm shifts in malaria parasite biochemistry and anti-malarial chemotherapy

Namita Surolia, Satish P. RamachandraRao, Avadhesha Surolia

Journal:

Year:

2002

Language:

english

File:

PDF, 151 KB

english, 2002

2

One Step Synthesis of Novel Antimicrobial 2-Hydroxy Diaryl Ethers Through Domestic Microwave Heating.

Sanjay Kumar, Mili Kapoor, Namita Surolia, Avadhesha Surolia

Journal:

Year:

2004

File:

PDF, 79 KB

2004

3

β-Ketoacyl-ACP synthase I/II from Plasmodium falciparum (PfFabB/F)—Is it B or F?

Shilpi Sharma, Shailendra Kumar Sharma, Namita Surolia, Avadhesha Surolia

Journal:

Year:

2009

Language:

english

File:

PDF, 136 KB

english, 2009

4

Evolutionary significance of self-acylation property in acyl carrier proteins

Ashish Misra, Namita Surolia, Avadhesha Surolia

Journal:

Year:

2009

Language:

english

File:

PDF, 308 KB

english, 2009

5

Triclosan inhibit the growth of the late liver-stage of Plasmodium

Agam Prasad Singh, Namita Surolia, Avadhesha Surolia

Journal:

Year:

2009

Language:

english

File:

PDF, 316 KB

english, 2009

6

Design, development, synthesis, and docking analysis of 2′-substituted triclosan analogs as inhibitors for Plasmodium falciparum Enoyl-ACP reductase

Neha Kapoor, Tanushree Banerjee, Ponnusamy Babu, Koustav Maity, Namita Surolia, Avadhesha Surolia

Journal:

Year:

2009

Language:

english

File:

PDF, 284 KB

english, 2009

7

SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase

Gyanendra Kumar, Tanushree Banerjee, Neha Kapoor, Namita Surolia, Avadhesha Surolia

Journal:

Year:

2010

Language:

english

File:

PDF, 418 KB

english, 2010

8

X-ray crystallographic analysis of the complexes of enoyl acyl carrier protein reductase of Plasmodium falciparum with triclosan variants to elucidate the importance of different functional groups in enzyme inhibition

Koustav Maity, Saligram Prabhakar Bhargav, Banumathi Sankaran, Namita Surolia, Avadhesha Surolia, Kaza Suguna

Journal:

Year:

2010

Language:

english

File:

PDF, 378 KB

english, 2010

9

Effect of substrate binding loop mutations on the structure, kinetics, and inhibition of enoyl acyl carrier protein reductase from plasmodium falciparum

Koustav Maity, Tanushree Banerjee, Narayanappa Prabakaran, Namita Surolia, Avadhesha Surolia, Kaza Suguna

Journal:

Year:

2011

Language:

english

File:

PDF, 713 KB

english, 2011

10

Effect of substrate binding loop mutations on the structure, kinetics, and inhibition of enoyl acyl carrier protein reductase from plasmodium falciparum

Koustav Maity, Tanushree Banerjee, Narayanappa Prabakaran, Namita Surolia, Avadhesha Surolia, Kaza Suguna

Journal:

Year:

2011

File:

PDF, 104 KB

2011

11

Benzothiophene carboxamide derivatives as novel antimalarials

Tanushree Banerjee, Neha Kapoor, Namita Surolia, Avadhesha Surolia

Journal:

Year:

2011

Language:

english

File:

PDF, 251 KB

english, 2011

12

Benzothiophene carboxamide derivatives as inhibitors of Plasmodium falciparum enoyl-ACP reductase

Tanushree Banerjee, Shailendra Kumar Sharma, Neha Kapoor, Vishnu Dwivedi, Namita Surolia, Avadhesha Surolia

Journal:

Year:

2011

Language:

english

File:

PDF, 419 KB

english, 2011

13

15-deoxyspergualin hinders physical interaction between basic residues of transit peptide in PfENR and Hsp70-1

Tanushree Banerjee, Rajiv Ranjan Singh, Sarika Gupta, Avadhesha Surolia, Namita Surolia

Journal:

Year:

2012

Language:

english

File:

PDF, 532 KB

english, 2012

14

Novel diphenyl ethers: Design, docking studies, synthesis and inhibition of enoyl ACP reductase of Plasmodium falciparum and Escherichia coli

Manmohan Chhibber, Gyanendra Kumar, Prasanna Parasuraman, T.N.C. Ramya, Namita Surolia, Avadhesha Surolia

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 412 KB

english, 2006

15

Synthesis and exploration of novel curcumin analogues as anti-malarial agents

Satyendra Mishra, Krishanpal Karmodiya, Namita Surolia, Avadhesha Surolia

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 191 KB

english, 2008

16

Design, synthesis, and application of novel triclosan prodrugs as potential antimalarial and antibacterial agents

Satyendra Mishra, Krishanpal Karmodiya, Prasanna Parasuraman, Avadhesha Surolia, Namita Surolia

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 413 KB

english, 2008

17

Self-Acylation Properties of Type II Fatty Acid Biosynthesis Acyl Carrier Protein

Ashish Misra, Shailendra Kumar Sharma, Namita Surolia, Avadhesha Surolia

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 842 KB

english, 2007

18

Analysis of proteins with the 'hot dog' fold: Prediction of function and identification of catalytic residues of hypothetical proteins

Lakshmi S Pidugu, Koustav Maity, Karthikeyan Ramaswamy, Namita Surolia, Kaza Suguna

Journal:

BMC Structural Biology

Year:

2009

Language:

english

File:

PDF, 6.70 MB

english, 2009

19

A unique and differential effect of denaturants on cofactor mediated activation of Plasmodium falciparum β-ketoacyl-ACP reductase

Krishanpal Karmodiya, Namita Surolia

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2008

Language:

english

File:

PDF, 532 KB

english, 2008

20

Triclosan and fatty acid synthesis inPlasmodium falciparum: New weapon for an old enemy

Gurpur Praveen Bhat, Namita Surolia

Journal:

Journal of Biosciences

Year:

2001

Language:

english

File:

PDF, 28 KB

english, 2001

21

NMR Assignment of the Holo-ACP from Malaria ParasitePlasmodium Falciparum

Alok Kumar Sharma, Shailendra Kumar Sharma, Namita Surolia, Siddhartha P. Sarma

Journal:

Journal of Biomolecular NMR

Year:

2005

Language:

english

File:

PDF, 184 KB

english, 2005

22

Backbone chemical shift assignments of the acyl-acyl carrier protein intermediates of the fatty acid biosynthesis pathway ofPlasmodium falciparum

Santosh Kumar Upadhyay, Ashish Misra, Namita Surolia, Avadhesha Surolia, Monica Sundd

Journal:

Biomolecular NMR Assignments

Year:

2010

Language:

english

File:

PDF, 226 KB

english, 2010

23

Erratum to: Backbone chemical shift assignments of the acyl-acyl carrier protein intermediates of the fatty acid biosynthesis pathway ofPlasmodium falciparum

Santosh Kumar Upadhyay, Ashish Misra, Namita Surolia, Avadhesha Surolia, Monica Sundd

Journal:

Biomolecular NMR Assignments

Year:

2010

Language:

english

File:

PDF, 95 KB

english, 2010

24

Analyses of co-operative transitions in Plasmodium falciparumβ-ketoacyl acyl carrier protein reductase upon co-factor and acyl carrier protein binding

Krishanpal Karmodiya, Namita Surolia

Journal:

Year:

2006

Language:

english

File:

PDF, 366 KB

english, 2006

25

Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein : Role of the 4′-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein

Rahul Modak, Sharmistha Sinha, Namita Surolia

Journal:

Year:

2007

Language:

english

File:

PDF, 1016 KB

english, 2007

26

Deciphering the key residues in Plasmodium falciparumβ-ketoacyl acyl carrier protein reductase responsible for interactions with Plasmodium falciparum acyl carrier protein

Krishanpal Karmodiya, Rahul Modak, Nirakar Sahoo, Syed Sajad, Namita Surolia

Journal:

Year:

2008

Language:

english

File:

PDF, 625 KB

english, 2008

27

10.1038/84612

Surolia, Namita, Surolia, Avadhesha

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 1.78 MB

english, 2001

28

Reply to: "Triclosan is minimally effective in rodent malaria models"

Surolia, Namita, Surolia, Avadhesha

Journal:

Nature Medicine

Year:

2011

Language:

english

File:

PDF, 119 KB

english, 2011

29

Mutational analysis of the triclosan-binding region of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum

KAPOOR, Mili, GOPALAKRISHNAPAI, Jayashree, SUROLIA, Namita, SUROLIA, Avadhesha

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 560 KB

english, 2004

30

Conformational stability and thermodynamic characterization of homotetrameric Plasmodium falciparum β-ketoacyl-ACP reductase

Krishanpal Karmodiya, Syed Sajad, Sharmistha Sinha, Koustav Maity, Kaza Suguna, Namita Surolia

Journal:

Year:

2007

Language:

english

File:

PDF, 1.17 MB

english, 2007

31

Discovery of a Rhodanine Class of Compounds as Inhibitors of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase

Kumar, Gyanendra, Parasuraman, Prasanna, Sharma, Shailendra Kumar, Banerjee, Tanushree, Karmodiya, Krishanpal, Surolia, Namita, Surolia, Avadhesha

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 369 KB

english, 2007

32

On the relationship of thermodynamic parameters with the buried surface area in protein-ligand complex formation

Netai C. Singha, Namita Surolia, A. Surolia

Journal:

Bioscience Reports

Year:

1996

Language:

english

File:

PDF, 509 KB

english, 1996

33

Receptor-mediated targeting of toxins to intraerythrocytic parasite Plasmodium falciparum

Journal:

Advanced Drug Delivery Reviews

Year:

2000

Language:

english

File:

PDF, 310 KB

english, 2000

34

Binding of 4-methylumbelliferyl β-d-galactopyranoside to Momordica charantia Lectin : Fluorescence-Quenching Studies

M. Islam KHAN, Tripti MAZUMDER, Debkumar PAIN, Namita GAUR, Avadhesha SUROLIA

Journal:

Year:

1981

Language:

english

File:

PDF, 542 KB

english, 1981

35

The Physicochemical Properties of the Galactose-Specific Lectin from Momordica charantia

Tripti MAZUMDER, Namita GAUR, Avadhesha SUROLIA

Journal:

Year:

1981

Language:

english

File:

PDF, 804 KB

english, 1981

36

Fluorescence Polarization as a Tool to Study Lectin-Sugar Interaction : An Investigation of the Binding of 4-Methylumbelliferyl β-d-Galactopyranoside to Abrus precatorious Agglutinin

M. Islam KHAN, Avadhesha SUROLIA, Namita SUROLIA, Mathew K. MATHEW, Padmnabhan BALARAM

Journal:

Year:

1981

Language:

english

File:

PDF, 420 KB

english, 1981

37

Synthesis and Evaluation of Substituted Pyrazoles: Potential Antimalarials Targeting the Enoyl‐ACP Reductase of Plasmodium Falciparum

Kumar, Sanjay, Kumar, Gyanendra, Kapoor, Mili, Surolia, Avadhesha, Surolia, Namita

Journal:

Synthetic Communications

Year:

2006

Language:

english

File:

PDF, 245 KB

english, 2006

38

Interaction of Chloroquine and Its Analogues with Heme: An Isothermal Titration Calorimetric Study

Kiran Bachhawat, Celestine J. Thomas, Namita Surolia, Avadhesha Surolia

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 66 KB

english, 2000

39

Structural Basis for Triclosan and NAD Binding to Enoyl-ACP Reductase of Plasmodium falciparum

Kaza Suguna, Avadhesha Surolia, Namita Surolia

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 110 KB

english, 2001

40

Kinetic Determinants of the Interaction of Enoyl-ACP Reductase from Plasmodium falciparum with Its Substrates and Inhibitors

Mili Kapoor, M Jamal Dar, Avadhesha Surolia, Namita Surolia

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 141 KB

english, 2001

41

De novo biosynthesis of heme offers a new chemotherapeutic target in the human malarial parasite

Namita Surolia, Govindarajan Padmanaban

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 394 KB

english, 1992

42

Mechanism of foetal wastage following immunoneutralization of riboflavin carrier protein in the pregnant rat: disturbances in flavin coenzyme levels

Kavita Krishnamurthy, Namita Surolia, P.Radhakantha Adiga

Journal:

Year:

1984

Language:

english

File:

PDF, 462 KB

english, 1984

43

Cell surface receptor directed targeting of toxin to human malaria parasite, Plasmodium falciparum

Namita Surolia, Sandra Misquith

Journal:

Year:

1996

Language:

english

File:

PDF, 583 KB

english, 1996

44

A novel approach for over-expression, characterization, and isotopic enrichment of a homogeneous species of acyl carrier protein from Plasmodium falciparum

Shailendra Kumar Sharma, Rahul Modak, Shilpi Sharma, Alok Kumar Sharma, Siddhartha P. Sarma, Avadhesha Surolia, Namita Surolia

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 491 KB

english, 2005

45

Polyamine synthesis and salvage pathways in the malaria parasite Plasmodium falciparum

T.N.C. Ramya, Namita Surolia, Avadhesha Surolia

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 291 KB

english, 2006

46

15-Deoxyspergualin modulates Plasmodium falciparum heat shock protein function

T.N.C. Ramya, Namita Surolia, Avadhesha Surolia

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

47

Epigallocatechin gallate is a slow-tight binding inhibitor of enoyl-ACP reductase from Plasmodium falciparum

Tanushree Banerjee, Shailendra Kumar Sharma, Namita Surolia, Avadhesha Surolia

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 274 KB

english, 2008

48

Partial molar volumes of acyl carrier proteins are related to their states of acylation

Sarika Gupta, Rahul Modak, Namita Surolia, Avadhesha Surolia

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 443 KB

english, 2009

49

Crystal structure of dimeric FabZ of Plasmodium falciparum reveals conformational switching to active hexamers by peptide flips

P. Lakshmi Swarnamukhi, Shailendra Kumar Sharma, Preeti Bajaj, Namita Surolia, Avadhesha Surolia, Kaza Suguna

Journal:

Year:

2006

Language:

english

File:

PDF, 465 KB

english, 2006

50

Structural Basis for the Variation in Triclosan Affinity to Enoyl Reductases

Lakshmi Swarnamukhi Pidugu, Mili Kapoor, Namita Surolia, Avadhesha Surolia, Kaza Suguna

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 572 KB

english, 2004